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Master Guide: Testing, Detox & Co-Infection Protocols

I. Essential Tests for Co-Infections

(Functional medicine tests > standard labs)

Infection TypeKey TestsBest Sample
Lyme & Co-infectionsIGeneX Immunoblot, Vibrant Wellness Tickborne Panel, FISH test for BartonellaBlood, urine
Mold (CIRS)Mycotoxin panels (Great Plains/RealTime Labs), MARCoNS nasal swab, C4a/MSHUrine, nasal swab, blood
Viruses (EBV/CMV/HHV-6)Early Antigen (EA) IgG, PCR viral load, Avidity testingBlood
H. pyloriGI-MAP stool PCR, Urea Breath TestStool, breath
ParasitesGI-MAP + BioFire PCR, Babesia FISH, O&P x3Stool, blood
SIBOLactulose Breath Test (3-hour)Breath
Dental InfectionsCone Beam CT, Oravital® bacterial cultureSaliva, imaging
Endotoxins/LPSEndoCab IgG, CD14 markersBlood
Fungal Infectionsβ-D-Glucan, Galactomannan, Histoplasma urine antigenBlood, urine

Critical Tip: Always run genetic detox panels (e.g., MTHFR, GST, SOD) to personalize detox protocols.


II. Detox Management: Surviving Herxheimer Reactions

Herx Reactions = Jarisch-Herxheimer response: Toxin flood from dying pathogens causing fatigue, pain, brain fog, or flu-like symptoms.

Detox ToolPurposeProtocol
BINDERSTrap toxins in gut– Mycotoxins: Cholestyramine, Okra Pepsin
– General: Zeolite, charcoal (take 2hrs away from meds)
Liver SupportBoost glutathione phase I/II detoxNAC (1,800mg/day), Milk Thistle, TUDCA
Lymphatic DrainageReduce inflammation/swellingManual drainage, rebounding, burdock root
SweatingExpel toxins via skinInfrared sauna 3x/week + electrolyte replenishment
Kidney FlushClear toxin-loaded bloodDandelion tea, magnesium citrate, hydration

Golden Rules:

  1. Start antimicrobials at 10-25% dose and increase weekly.
  2. “Pulse” treatments (5 days on, 2 days off) to limit toxin buildup.
  3. If Herx hits: Stop antimicrobials, double binders/water, rest 48h.

III. Co-Infection Protocols by Cluster

A. Cluster: LYME + MOLD + EBV

  • Phase 1 (Prep):
    • Remove mold exposure (HEPA filters, remediation).
    • Binders + drainage support (3 weeks).
  • Phase 2 (Kill):
    • Lyme: Japanese knotweed + cryptolepis (herbal) or disulfiram (pharma).
    • Mold: Itraconazole (if Aspergillus) or cholestyramine + glutathione.
    • EBV: Monolaurin (6g/day) + high-dose zinc.
  • Phase 3 (Repair:
    • Mitochondrial support (CoQ10, NAD+), neural retraining.

B. Cluster: H. PYLORI + SIBO + CANDIDA

  • Phase 1 (Starve):
    • Low-FODMAP diet + biofilm disruptors (interfase plus).
  • Phase 2 (Attack):
    • H. pylori: Mastic gum (2g/day) + bismuth.
    • SIBO: Berberine (1,500mg/day) + allicin.
    • Candida: Caprylic acid + nystatin.
  • Phase 3 (Rebuild):
    • Soil-based probiotics, glutamine for gut lining.

C. Cluster: DENTAL INFECTIONS + PARASITES

  1. Dental first:
    • Remove infected teeth/implants (biological dentist).
    • 2 weeks post-op: Ozone therapy + lymphatic massage.
  2. Then parasites:
    • Alinia (nitazoxanide) + mimosa pudica seed.
    • Epsom salt baths daily during treatment.

D. Cluster: LONG COVID + REACTIVATED VIRUSES

  • Core Protocol:
    • Antivirals: L-lysine (3g/day) + olive leaf.
    • Spike protein clearance: Natto-serra, bromelain.
    • Autonomic support: Vagus nerve stimulation, IV phospholipids.

Critical Principles for Success

  1. Order Matters:
    • Drainage > Dental > Mold > Infections > Viruses.
  2. Never Detox on a Sludge Highway:
    • Open drainage pathways (bowels, kidneys, skin) BEFORE killing pathogens.
  3. Track ONE Symptom:
    • Choose a “North Star” symptom (e.g., fatigue severity) to gauge progress.
  4. When Stuck, Test For:
    • Heavy metals (hair test), scar tissue (NRT), or limbic system dysfunction (DNRS).